Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.33 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566403 | 0.87 | KDM4E (0.43) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8881243 | 0.86 | LATS1 (0.37) | KDM4EALDH1A1LMNALATS1HTR2C | |
| SCHEMBL8881374 | 0.83 | LMNA (0.39) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8881120 | 0.82 | ALDH1A1 (0.55) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8881299 | 0.80 | LATS1 (0.33) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8882227 | 0.78 | KDM4E (0.57) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8881905 | 0.77 | TOP2A (0.39) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8882301 | 0.75 | TOP2A (0.37) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8882157 | 0.75 | TOP2A (0.49) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9355301 | 0.72 | LMNA (0.39) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663331-A | BACTERICIDES | IL-DONG PHARM. CO., LTD. (KR) | 1997-09-02 | — | — | US | disclosed |
| EP-0623136-A1 | NOVEL CEPHALOSPORIN COMPOUNDS | IL-DONG PHARM. CO., LTD. (KR) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993015084-A1 | NOVEL CEPHALOSPORIN COMPOUNDS | IL-DONG PHARM. CO., LTD. (KR) | 1993-08-05 | — | — | WO | disclosed |