SCHEMBL8881975

SCHEMBL8881975

CCCCN1CCC[C@H](NC(=O)OC(C)(C)C)CC1=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CTSK P43235 2/20 0.43
BTK Q06187 2/20 0.43
JAK3 P52333 1/20 0.42
DPP4 P27487 1/20 0.41
KCNA3 P22001 1/20 0.41
KMT2A Q03164 1/20 0.40
DRD2 P14416 2/20 0.39
EPHX1 P07099 1/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
PRSS1 P07477 1/20 0.39
MAP4K4 O95819 2/20 0.37
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098249 0.86 CA1 (0.46) L3MBTL1CA1CA2CTSKBTK
SCHEMBL7471624 0.79 MMP1 (0.49) L3MBTL1F2F10PRSS1GAA
SCHEMBL28969100 0.75 L3MBTL1 (0.44) L3MBTL1CA1CA2CTSKBTK
SCHEMBL25022225 0.75 L3MBTL1 (0.44) L3MBTL1CA1CA2CTSKBTK
SCHEMBL17207700 0.75 CTSK (0.56) L3MBTL1CA1CA2CTSKBTK
SCHEMBL15130652 0.74 F2 (0.54) L3MBTL1CA1CA2CTSKBTK
SCHEMBL7095712 0.74 CTSK (0.49) L3MBTL1CA1CA2CTSKBTK
SCHEMBL13108631 0.74 CTSK (0.45) L3MBTL1CA1CA2CTSKBTK
SCHEMBL21733136 0.74 CA1 (0.56) L3MBTL1CA1CA2CTSKBTK
SCHEMBL29255478 0.74 CA1 (0.56) L3MBTL1CA1CA2CTSKBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5672598-A MATRIX METALLOPROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1997-09-30 US disclosed