Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.39 |
| ▸ | MME | P08473 | 8/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881495 | 0.86 | MME (0.45) | ACEMMECPA1ACE2 | |
| SCHEMBL9227091 | 0.73 | ACE (0.56) | ACEMME | |
| SCHEMBL8883149 | 0.73 | ACE (0.56) | ACEMME | |
| SCHEMBL8882317 | 0.72 | MMEL1 (0.36) | — | |
| SCHEMBL8881756 | 0.68 | ALDH1A1 (0.36) | — | |
| SCHEMBL14865944 | 0.60 | BRD4 (0.47) | — | |
| SCHEMBL11109826 | 0.55 | CA12 (0.44) | CA12CA9 | |
| SCHEMBL8673301 | 0.55 | ALDH1A1 (0.48) | HDAC1HDAC6 | |
| SCHEMBL522099 | 0.55 | ALDH1A1 (0.50) | CA12CA9 | |
| SCHEMBL24879174 | 0.55 | TAAR1 (0.70) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679671-A | ANGIOTENSIN 1-CONVERTING ENZYME INHIBITOR, VASOPRESSIN ANTAGONISM AND ATRIAL NAUTRIURETIC PEPTIDE HYDROLASE INHIBITOR | EISAI CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |