Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673747 | 0.83 | NAMPT (0.45) | ALDH1A1NPC1MITFHTTRAB9A | |
| SCHEMBL8675155 | 0.68 | DPP8 (0.41) | ALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL14306400 | 0.67 | HSD17B3 (0.49) | NPC1RAB9ASMN1; SMN2ABHD6HSD17B3 | |
| SCHEMBL28019824 | 0.66 | LIPE (0.50) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL11420444 | 0.66 | NAMPT (0.44) | NPC1MITFRAB9ATMEM97SIGMAR1 | |
| SCHEMBL12630783 | 0.66 | TMEM97 (0.47) | ABHD6HSD17B3BACE1HDAC4UCHL1 | |
| SCHEMBL2330263 | 0.65 | ALDH1A1 (1.00) | ALDH1A1NPC1MITFHTTRAB9A | |
| SCHEMBL4003283 | 0.65 | MITF (0.72) | ALDH1A1NPC1MITFHTTRAB9A | |
| SCHEMBL8677167 | 0.65 | ACACB (0.43) | — | |
| SCHEMBL8673285 | 0.65 | MTNR1A (0.53) | ALDH1A1HTTSMN1; SMN2ABHD6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |