Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883025 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8882717 | 0.78 | TOP2A (0.41) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22579210 | 0.78 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Iodide SCHEMBL9805908 | 0.78 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5566403 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9678335 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL4629781 | 0.74 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL48002 | 0.74 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10808425 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10886382 | 0.74 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663331-A | BACTERICIDES | IL-DONG PHARM. CO., LTD. (KR) | 1997-09-02 | — | — | US | disclosed |
| US-5639885-A | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0293071-B1 | REDOX AMINO ACIDS AND PEPTIDES CONTAINING THEM | UNIVERSITY OF FLORIDA (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1993015084-A1 | NOVEL CEPHALOSPORIN COMPOUNDS | IL-DONG PHARM. CO., LTD. (KR) | 1993-08-05 | — | — | WO | disclosed |
| US-5079366-A | To derivatize pharmaceutical peptides for transport across the blood/brain barrier | UNIVERSITY OF FLORIDA (US) | 1992-01-07 | — | — | US | disclosed |
| US-4888427-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX SYSTEM | UNIVERSITY OF FLORIDA (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0293071-A1 | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1988-11-30 | — | — | EP | disclosed |