Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199640 | 0.91 | ALDH1A1 (0.51) | POLBALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL8882276 | 0.84 | L3MBTL1 (0.57) | RAB9ASMN1; SMN2TSHRKDM4EKMT2A | |
| SCHEMBL13946711 | 0.82 | RAB9A (0.55) | RAB9AALDH1A1KMT2A | |
| SCHEMBL5872083 | 0.82 | L3MBTL1 (0.67) | RAB9AALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL7174354 | 0.82 | L3MBTL1 (0.46) | RAB9AALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL10504904 | 0.82 | KMT2A (0.48) | RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL2774412 | 0.81 | L3MBTL1 (0.66) | RAB9APOLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13639145 | 0.81 | ALDH1A1 (0.48) | RAB9APOLBALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL1254047 | 0.80 | L3MBTL1 (0.69) | RAB9APOLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1647525 | 0.78 | HRH1 (0.52) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |