Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284055 | 0.94 | PARP10 (0.41) | ITGB3ITGA2BPARP10PDE4APDE4B | |
| SCHEMBL7276387 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL7273468 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| Water SCHEMBL8882300 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL7275504 | 0.88 | ABCB1 (0.45) | ITGB3ITGA2BOPRM1ALDH1A1LMNA | |
| SCHEMBL7276469 | 0.88 | ABCB1 (0.45) | ITGB3ITGA2BOPRM1ALDH1A1LMNA | |
| SCHEMBL7275542 | 0.87 | ALDH1A1 (0.40) | OPRK1OPRM1OPRD1KCNH2ALDH1A1 | |
| SCHEMBL7280302 | 0.87 | ALDH1A1 (0.40) | OPRM1ALDH1A1LMNAMAPTTSHR | |
| Water SCHEMBL8881986 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7276130 | 0.86 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |