Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881749 | 0.86 | NPSR1 (0.43) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8882202 | 0.85 | CASP3 (0.46) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9233093 | 0.84 | L3MBTL1 (0.49) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8881736 | 0.82 | CASP3 (0.46) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL26965325 | 0.77 | RIPK1 (0.44) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17925766 | 0.77 | GAA (0.51) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9233372 | 0.76 | KDM4E (0.41) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8881539 | 0.75 | NPSR1 (0.41) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8881874 | 0.74 | RAB9A (0.40) | KMT2ACYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8882513 | 0.74 | CASP3 (0.47) | KMT2ACYP2D6CYP2C9CYP2C19PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677316-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |