SCHEMBL888339

SCHEMBL888339

CCOC(=O)C(COC)C(C)(C)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.34
ALDH1A1 P00352 2/20 0.33
METAP2 P50579 1/20 0.33
METAP1 P53582 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
CPB2 Q96IY4 1/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888627 0.85 MMP8 (0.34) MMP8ALDH1A1METAP2METAP1LMNA
SCHEMBL888640 0.85 SMN1; SMN2 (0.34) LMNASMN1; SMN2
SCHEMBL819040 0.82 ALDH1A1 (0.37) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL888625 0.81 ALDH1A1 (0.36) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL820136 0.79 ALDH1A1 (0.34) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL22135562 0.78 MMP8 (0.38) MMP8ALDH1A1METAP2METAP1LMNA
SCHEMBL974546 0.78 GAA (0.40) MMP8ALDH1A1METAP2METAP1HSD17B10
SCHEMBL819723 0.77
SCHEMBL888389 0.76 TSHR (0.36) MMP8ALDH1A1METAP2METAP1LMNA
SCHEMBL14906992 0.74 ALDH1A1 (0.40) MMP8ALDH1A1METAP2METAP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed