SCHEMBL888529

SCHEMBL888529

CCOC(=O)C(C(CC(C)C)OCC)C(C)(C)CC

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.34
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888408 0.87 MMP8 (0.36) MMP8LMNAALDH1A1HSD17B10
SCHEMBL888612 0.76 ALDH1A1 (0.33) MMP8LMNAALDH1A1HSD17B10
SCHEMBL888621 0.75 ALDH1A1 (0.32) MMP8LMNAALDH1A1HSD17B10
SCHEMBL888601 0.74 ALDH1A1 (0.38) MMP8LMNAALDH1A1HSD17B10TP53
SCHEMBL14621277 0.74 MMP8 (0.39) MMP8LMNAALDH1A1HSD17B10TP53
SCHEMBL820722 0.73 LMNA (0.32) LMNA
SCHEMBL7213719 0.67 ALDH1A1 (0.42) MMP8LMNAALDH1A1HSD17B10
SCHEMBL14770006 0.67 ALDH1A1 (0.46) MMP8LMNAALDH1A1HSD17B10
SCHEMBL15034664 0.67 ALDH1A1 (0.46) MMP8LMNAALDH1A1HSD17B10
SCHEMBL13821863 0.67 ALDH1A1 (0.46) MMP8LMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed