Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394842 | 0.94 | SLC6A2 (0.40) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9393081 | 0.93 | SLC6A2 (0.40) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9050314 | 0.90 | SLC6A2 (0.42) | HSD11B1SLC6A2SLC6A4ALDH1A1HTT | |
| SCHEMBL9397103 | 0.88 | SLC6A2 (0.39) | HSD11B1SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL9397041 | 0.88 | ALDH1A1 (0.45) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9396981 | 0.85 | HSD11B1 (0.36) | HSD11B1SLC6A2SLC6A4ALDH1A1HTT | |
| SCHEMBL9392945 | 0.85 | ALDH1A1 (0.39) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL8884514 | 0.84 | HSD11B1 (0.41) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9397063 | 0.83 | HSD11B1 (0.37) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9396980 | 0.79 | HSD11B1 (0.39) | HSD11B1SLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677324-A | MUSCLE RELAXANTS | PFIZER INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1994020491-A1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |