Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397103 | 0.91 | SLC6A2 (0.39) | SLC6A2SLC6A4HSD11B1ALDH1A1LMNA | |
| SCHEMBL8885300 | 0.90 | HSD11B1 (0.39) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9392945 | 0.85 | ALDH1A1 (0.39) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9396981 | 0.85 | HSD11B1 (0.36) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9394842 | 0.84 | SLC6A2 (0.40) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9393081 | 0.83 | SLC6A2 (0.40) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9397041 | 0.80 | ALDH1A1 (0.45) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9054344 | 0.80 | HSD11B1 (0.40) | SLC6A2SLC6A4HSD11B1ALDH1A1LMNA | |
| SCHEMBL9050508 | 0.77 | HIF1A (0.43) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT | |
| SCHEMBL9397063 | 0.77 | HSD11B1 (0.37) | SLC6A2SLC6A4HSD11B1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690855-B1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LTD (GB) | 1996-12-18 | — | — | EP | disclosed |
| WO-1994020491-A1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |