Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050314 | 0.91 | SLC6A2 (0.42) | SLC6A2SLC6A4QPCTQPCTLHSD11B1 | |
| SCHEMBL8885300 | 0.88 | HSD11B1 (0.39) | SLC6A2SLC6A4HSD11B1LMNAALDH1A1 | |
| SCHEMBL9392945 | 0.83 | ALDH1A1 (0.39) | SLC6A2SLC6A4HSD11B1TSHRALDH1A1 | |
| SCHEMBL9396981 | 0.83 | HSD11B1 (0.36) | SLC6A2SLC6A4SIGMAR1HSD11B1HRH3 | |
| SCHEMBL9394842 | 0.83 | SLC6A2 (0.40) | SLC6A2SLC6A4HSD11B1ALDH1A1MEN1 | |
| SCHEMBL9393081 | 0.82 | SLC6A2 (0.40) | SLC6A2SLC6A4HSD11B1ALDH1A1MEN1 | |
| SCHEMBL9397041 | 0.80 | ALDH1A1 (0.45) | SLC6A2SLC6A4HSD11B1ALDH1A1MEN1 | |
| SCHEMBL8886385 | 0.79 | HIF1A (0.42) | SLC6A2SLC6A4SIGMAR1QPCTQPCTL | |
| SCHEMBL9397063 | 0.76 | HSD11B1 (0.37) | SLC6A2SLC6A4HSD11B1MAPTTSHR | |
| SCHEMBL9396980 | 0.75 | HSD11B1 (0.39) | SLC6A2SLC6A4HSD11B1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994020491-A1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |