SCHEMBL8885808

SCHEMBL8885808

O=[PH](O)OCC(O[PH](=O)O)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GSR P00390 1/20 0.38
CYP2D6 P10635 3/20 0.36
CYP1A2 P05177 1/20 0.36
PKM P14618 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KMT2A Q03164 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SRC P12931 1/20 0.32
LMNA P02545 2/20 0.31
HRH1 P35367 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
ACP3 P15309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887656 0.81 CA12 (0.44) POLBCYP2D6CYP1A2PKMSMN1; SMN2
SCHEMBL28980079 0.80 LMNA (0.44) POLBGSRKMT2ALMNA
SCHEMBL297993 0.79 EPHX1 (0.43) CYP1A2PKMSMN1; SMN2ACP3
SCHEMBL29199959 0.77 THRB (0.37) GSRCYP2D6CYP1A2PKMSMN1; SMN2
SCHEMBL5013275 0.77 THRB (0.47) POLBGSRCYP2D6CYP1A2PKM
SCHEMBL2820605 0.76 TAAR1 (0.44) POLBCYP2D6CYP1A2PKMSMN1; SMN2
SCHEMBL28141976 0.76 SCN4A (0.52) CYP2D6CYP1A2PKMSMN1; SMN2NPSR1
SCHEMBL29200771 0.76 RIPK1 (0.39) POLBGSRKMT2ALMNAHRH1
SCHEMBL15898694 0.75 POLB (0.43) POLBCA2LMNA
SCHEMBL11773872 0.75 GSR (0.35) POLBGSRCYP2D6CYP1A2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110267798-B Method of manufacturing an object by additive manufacturing using a polycarbonate build material having improved flow capability 科思创德国股份有限公司 2022-05-27 CN disclosed
CN-107207864-B Flame-resistant moulding compositions containing glass fibres, containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2021-03-02 CN disclosed
CN-107207863-B Flame-resistant moulding compositions containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2021-02-19 CN disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
US-20120244359-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
US-5693697-A Flame-resistant polycarbonate moulding-compositions BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed