Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 5/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222485 | 0.80 | DHODH (0.40) | DHODHMYCNR4A1ALDH1A1RECQL | |
| SCHEMBL3460245 | 0.79 | DHODH (0.41) | DHODHMYCNR4A1ALDH1A1L3MBTL1 | |
| SCHEMBL3458495 | 0.78 | DHODH (0.40) | DHODHMYCNR4A1ALDH1A1L3MBTL1 | |
| SCHEMBL3459620 | 0.77 | MAPT (0.47) | ALDH1A1L3MBTL1RECQLKDM4ETSHR | |
| SCHEMBL2777482 | 0.74 | NFKB1 (0.41) | ALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL3459262 | 0.73 | DHODH (0.37) | DHODHALDH1A1L3MBTL1RECQLNOTUM | |
| SCHEMBL1892990 | 0.72 | ALDH1A1 (0.43) | DHODHMYCNR4A1ALDH1A1L3MBTL1 | |
| SCHEMBL543144 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHR | |
| SCHEMBL544288 | 0.71 | KDM4E (0.41) | ALDH1A1KDM4ETSHR | |
| SCHEMBL3459213 | 0.71 | KDM5A (0.38) | DHODHALDH1A1RECQLKDM4ESPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691347-A | ANGIOTENSIN II INHIBITORS AND VASOCONSTRICTION | ROUSSEL UCLAF (FR) | 1997-11-25 | — | — | US | disclosed |