Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PSMB11 | A5LHX3 | 11/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 11/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 11/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 11/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 11/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 11/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 11/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 11/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 11/20 | 0.39 |
| ▸ | PSMA5 | P28066 | 11/20 | 0.39 |
| ▸ | PSMB4 | P28070 | 11/20 | 0.39 |
| ▸ | PSMB6 | P28072 | 11/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 11/20 | 0.39 |
| ▸ | PSMB3 | P49720 | 11/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 11/20 | 0.39 |
| ▸ | PSMA6 | P60900 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301913 | 1.00 | POLB (0.40) | POLBEIF4HMAPTPSMB11PSMA7 | |
| SCHEMBL7311575 | 0.91 | MAPK1 (0.44) | POLBEIF4HMAPTPSMB11PSMA7 | |
| SCHEMBL7311569 | 0.91 | MAPK1 (0.44) | POLBEIF4HMAPTPSMB11PSMA7 | |
| SCHEMBL7308007 | 0.90 | SMN1; SMN2 (0.45) | POLBEIF4HMAPTPSMB5ALDH1A1 | |
| SCHEMBL7313668 | 0.90 | SMN1; SMN2 (0.45) | POLBEIF4HMAPTPSMB5ALDH1A1 | |
| SCHEMBL8681379 | 0.89 | ALDH1A1 (0.37) | POLBEIF4HMAPTALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL7308817 | 0.88 | CTSL (0.42) | POLBEIF4HMAPTALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL7308810 | 0.88 | CTSL (0.42) | POLBEIF4HMAPTALDH1A1USP2 | |
| SCHEMBL7303780 | 0.80 | POLB (0.48) | POLBMAPTPSMB5ALDH1A1USP2 | |
| SCHEMBL7303804 | 0.80 | POLB (0.48) | POLBMAPTPSMB5ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |