Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887587 | 0.87 | KMT2A (0.40) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL9067904 | 0.85 | KMT2A (0.48) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL9724362 | 0.81 | PARP1 (0.36) | KMT2AALDH1A1MAPTHTTOPRK1 | |
| SCHEMBL1055212 | 0.76 | GPR139 (0.52) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL14417102 | 0.76 | GPR139 (0.52) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8597576 | 0.75 | ALDH1A1 (0.42) | GPR139KMT2AALDH1A1MAPTHTT | |
| Succinimide SCHEMBL8888235 | 0.74 | KMT2A (0.44) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8595095 | 0.73 | GPR139 (0.55) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL16135529 | 0.71 | ALDH1A1 (0.53) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL19034783 | 0.71 | GPR139 (0.54) | GPR139KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616692-A | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy | NEORX CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |