Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887585 | 0.85 | GPR139 (0.40) | KMT2AGPR139ALDH1A1MAPTHTT | |
| SCHEMBL8887587 | 0.85 | KMT2A (0.40) | KMT2AGPR139ALDH1A1MAPTHTT | |
| SCHEMBL3392049 | 0.74 | KDM4E (0.34) | GAAHTTKDM4ELMNA | |
| SCHEMBL5977694 | 0.72 | MGLL (0.42) | KMT2AGPR139ALDH1A1MAPTHTT | |
| SCHEMBL9067902 | 0.71 | PGR (0.36) | KMT2AALDH1A1MAPTGAAHTT | |
| SCHEMBL1520392 | 0.69 | KMT2A (0.58) | KMT2AGPR139ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9724362 | 0.69 | PARP1 (0.36) | KMT2AALDH1A1MAPTGAAHTT | |
| SCHEMBL18439047 | 0.69 | ALDH1A1 (0.42) | KMT2AALDH1A1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL11287633 | 0.67 | KMT2A (0.52) | KMT2AGPR139ALDH1A1MAPTHTT | |
| SCHEMBL15341566 | 0.66 | KMT2A (0.64) | KMT2AGPR139ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534497-A | RADIOPHARMACEUTICALS; MEDICAL DIAGNOSIS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5187264-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT MEDICAL, INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0250013-B1 | TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4849511-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0250013-A1 | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1987-12-23 | — | — | EP | disclosed |