Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29550444 | 0.79 | HTR2A (0.50) | ALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL8886446 | 0.78 | MGLL (0.45) | SMN1; SMN2HTT | |
| SCHEMBL8886064 | 0.78 | MMP2 (0.40) | ALDH1A1RAB9ASMN1; SMN2TDP1GAA | |
| SCHEMBL8308800 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1RAB9ASMN1; SMN2HTTTDP1 | |
| SCHEMBL516278 | 0.77 | TDP1 (0.56) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8309536 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1RAB9ASMN1; SMN2HTTTDP1 | |
| SCHEMBL8308799 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1RAB9ASMN1; SMN2HTTTDP1 | |
| SCHEMBL8308796 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1RAB9ASMN1; SMN2HTTTDP1 | |
| SCHEMBL5017678 | 0.76 | HTR2A (0.50) | ALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL25445958 | 0.76 | CARM1 (0.58) | ALDH1A1KMT2ATDP1LMNACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |