Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562422 | 0.84 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL8887683 | 0.78 | ESR1 (0.39) | ADORA2AADORA2B | |
| SCHEMBL8889178 | 0.75 | ADORA2A (0.41) | ADORA2AADORA2B | |
| SCHEMBL3628566 | 0.68 | — | — | |
| SCHEMBL6486543 | 0.67 | KMO (0.36) | ADORA2A | |
| SCHEMBL8226285 | 0.66 | DGAT1 (0.40) | ADORA2AADORA2B | |
| SCHEMBL9232701 | 0.64 | HTR2A (0.35) | — | |
| SCHEMBL14561774 | 0.62 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL26912128 | 0.61 | — | — | |
| SCHEMBL11976878 | 0.59 | DGAT1 (0.43) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |