Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749660 | 0.81 | L3MBTL1 (0.48) | L3MBTL1KMT2AMEN1KDM4EJAK2 | |
| SCHEMBL18704182 | 0.79 | KDM4E (0.62) | KMT2AMEN1KDM4EALDH1A1RECQL | |
| SCHEMBL534956 | 0.77 | L3MBTL1 (0.57) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29496331 | 0.77 | L3MBTL1 (0.57) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL318407 | 0.77 | KDM4E (0.60) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29420807 | 0.77 | KDM4E (0.60) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5459183 | 0.77 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11483348 | 0.74 | L3MBTL1 (0.51) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3639155 | 0.74 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3828701 | 0.74 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620974-A | ENZYME INHIBITOR, TREATS ACQUIRED IMMUNE DEFICIENCY SYNDROME(AIDS) | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-04-15 | — | — | US | disclosed |
| US-5366972-A | 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-4116965-A | STYRYL DYESTUFFS CONTAINING CERTAIN AMINO, CYANOPYRIDINE MOIETIES | CIBA-GEIGY CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |