Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888658 | 0.83 | ACHE (0.37) | ALDH1A1NPSR1PPARGPPARASMN1; SMN2 | |
| SCHEMBL8889815 | 0.81 | LDHA (0.43) | ALDH1A1NPSR1PPARGPPARATDP1 | |
| SCHEMBL945944 | 0.81 | CHRM1 (0.41) | ALDH1A1NPSR1PPARGPPARATDP1 | |
| SCHEMBL23091404 | 0.79 | PPARG (0.43) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL8888296 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1TDP1SMN1; SMN2TP53MAPT | |
| SCHEMBL7795001 | 0.75 | NR5A1 (0.51) | TP53 | |
| SCHEMBL13265662 | 0.72 | ALDH1A1 (0.44) | ALDH1A1NPSR1PPARGPPARATDP1 | |
| SCHEMBL8889564 | 0.72 | MRGPRX4 (0.39) | PPARG | |
| SCHEMBL4258180 | 0.71 | ALDH1A1 (0.43) | ALDH1A1NPSR1PPARGPPARATDP1 | |
| SCHEMBL10460179 | 0.71 | SLC6A4 (0.42) | ALDH1A1NPSR1PPARGPPARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |