SCHEMBL8890429

SCHEMBL8890429

O=c1[nH]cc(-c2n[nH]c3ccccc23)c(=O)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 4/20 0.50
IDO1 P14902 3/20 0.50
GAA P10253 2/20 0.50
TTK P33981 2/20 0.50
ALPL P05186 1/20 0.50
HPGD P15428 1/20 0.50
MAPK10 P53779 1/20 0.50
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
RAB9A P51151 1/20 0.47
CA12 O43570 1/20 0.47
PARP1 P09874 1/20 0.47
CA9 Q16790 1/20 0.47
ITK Q08881 2/20 0.45
FGFR1 P11362 1/20 0.45
FLT1 P17948 1/20 0.45
MAP2K4 P45985 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30272065 0.82 PDGFRB (0.53) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL17337955 0.82 PDGFRB (0.53) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL29053552 0.78 KDM4E (0.53) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL3712544 0.74 KDM4E (0.62) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL1672674 0.73 IDO1 (0.78) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL12501036 0.71 ROCK2 (0.56) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL31093732 0.71 DAO (0.49) ALDH1A1KDM4EIDO1GAATTK
SCHEMBL5328391 0.71 PRKCB (0.72) FLT1LRRK2PDGFRBAURKAPDPK1
SCHEMBL5801644 0.69 ALDH1A1 (0.64) ALDH1A1GAA
SCHEMBL3485414 0.69 ALDH1A1 (1.00) ALDH1A1KDM4EGAAHPGDPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997012884-A1 HERBICIDAL 6-HETEROCYCLIC INDAZOLE DERIVATIVES FMC CORPORATION (US) 1997-04-10 WO disclosed