Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.70 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.60 |
| ▸ | MERTK | Q12866 | 1/20 | 0.57 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891646 | 0.84 | PIN1 (0.55) | NPY5RPIN1AURKAJAK2AURKB | |
| SCHEMBL2591063 | 0.84 | NPY5R (1.00) | NPY5RPIN1AURKAMERTKABCG2 | |
| SCHEMBL9938046 | 0.84 | ABCG2 (0.80) | KDM1AABCC1ABCG2MEN1KMT2A | |
| Benzene SCHEMBL28899784 | 0.83 | MAPT (0.61) | PIN1KDM1ALRRK2ABCC1ABCG2 | |
| SCHEMBL4147023 | 0.83 | MAPT (0.61) | PIN1KDM1ALRRK2ABCC1ABCG2 | |
| Hydrochloric Acid SCHEMBL6039677 | 0.82 | NPY5R (0.96) | NPY5RPIN1AURKAABCG2MEN1 | |
| SCHEMBL8890734 | 0.81 | NPY5R (0.81) | NPY5RMERTKABCG2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8900449 | 0.81 | NPY5R (0.81) | NPY5RPIN1KDM1AMERTKMEN1 | |
| Hydrochloric Acid SCHEMBL8889510 | 0.80 | NPY5R (0.79) | NPY5RMERTKABCG2MEN1KMT2A | |
| SCHEMBL8898077 | 0.80 | NPY5R (0.84) | NPY5RMERTKABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |