Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890597 | 0.93 | ABCC8 (0.38) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8890090 | 0.92 | KEAP1 (0.39) | KEAP1NFE2L2GAATDP1L3MBTL1 | |
| SCHEMBL8891698 | 0.91 | GAA (0.39) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8891348 | 0.91 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11GAATDP1 | |
| SCHEMBL8890827 | 0.88 | ALDH1A1 (0.44) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8892315 | 0.86 | ABCC9 (0.33) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8890673 | 0.86 | NPSR1 (0.43) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8892165 | 0.85 | ABCC9 (0.37) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8890364 | 0.85 | ABCC9 (0.37) | KEAP1NFE2L2ABCC9ABCC8KCNJ11 | |
| SCHEMBL8893620 | 0.85 | ALDH1A1 (0.34) | KEAP1NFE2L2ABCC8GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |