Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890615 | 0.79 | HTT (0.51) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8889942 | 0.79 | HTT (0.48) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8887318 | 0.77 | KMT2A (0.52) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL6255367 | 0.72 | CYP2C9 (0.52) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL6258294 | 0.72 | EDNRB (0.53) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL30522544 | 0.72 | CYP1A2 (0.68) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8887875 | 0.71 | MEN1 (0.51) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10140278 | 0.71 | SMN1; SMN2 (0.48) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8889460 | 0.71 | MEN1 (0.48) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL30928895 | 0.71 | MEN1 (0.55) | MEN1HTTKMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |