Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 6/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890527 | 0.99 | POLB (0.64) | POLBTOP2ASLC2A1CACNA2D1GAA | |
| SCHEMBL11861178 | 0.92 | POLB (0.71) | POLBTOP2ASLC2A1CACNA2D1GAA | |
| Hydrochloric Acid SCHEMBL8890506 | 0.86 | POLB (0.59) | POLBTOP2ASLC2A1CACNA2D1GAA | |
| SCHEMBL11734758 | 0.83 | CASP6 (0.62) | POLBCASP6APPBCHEACHE | |
| SCHEMBL8890399 | 0.82 | CASP6 (0.52) | CASP6APPBCHEACHENPY1R | |
| SCHEMBL8890175 | 0.81 | PDE5A (0.55) | CASP6APPBCHEACHEALDH1A1 | |
| SCHEMBL12120415 | 0.81 | APP (0.65) | POLBTOP2ASLC2A1CACNA2D1GAA | |
| SCHEMBL8890083 | 0.81 | POLB (0.55) | POLBTOP2ASLC2A1CACNA2D1GAA | |
| SCHEMBL8908343 | 0.81 | POLB (0.55) | POLBTOP2ASLC2A1CACNA2D1GAA | |
| SCHEMBL8899454 | 0.80 | POLB (0.52) | POLBTOP2ASLC2A1CACNA2D1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020821-A1 | HETEROARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |