SCHEMBL8890399

SCHEMBL8890399

CNc1nc(NCCCCCCN)nc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.52
NPY1R P25929 1/20 0.52
NPY5R Q15761 1/20 0.52
ACHE P22303 9/20 0.51
BCHE P06276 4/20 0.51
APP P05067 3/20 0.51
RAD52 P43351 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8890389 0.85 ACHE (0.48) CASP6NPY5RACHEBCHEAPP
SCHEMBL11734758 0.84 CASP6 (0.62) CASP6NPY1RNPY5RACHEBCHE
SCHEMBL8890175 0.84 PDE5A (0.55) CASP6ACHEBCHEAPPRAD52
SCHEMBL8890767 0.82 POLB (0.61) CASP6NPY1RNPY5RACHEBCHE
SCHEMBL8892545 0.82 NPY5R (0.70) NPY1RNPY5RACHEAPP
SCHEMBL8893524 0.82 NPY5R (0.70) NPY1RNPY5RACHEAPP
SCHEMBL6039582 0.82 NPY5R (0.70) NPY1RNPY5RACHEAPP
Hydrochloric Acid SCHEMBL8890527 0.81 POLB (0.64) CASP6NPY1RNPY5RACHEBCHE
Hydrochloric Acid SCHEMBL8892586 0.81 NPY5R (0.68) NPY1RNPY5RACHEAPP
SCHEMBL8893023 0.80 NPY5R (0.51) NPY1RNPY5RACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997020821-A1 HETEROARYL DERIVATIVES NOVARTIS AG (CH) 1997-06-12 WO disclosed