Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891347 | 0.87 | CCKBR (0.43) | — | |
| SCHEMBL8890236 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1MAPTKMT2AGSK3B | |
| SCHEMBL8891676 | 0.83 | ALDH1A1 (0.37) | TSHRKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8890217 | 0.82 | GLA (0.36) | TSHRKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8888951 | 0.81 | SCN9A (0.48) | ALDH1A1 | |
| SCHEMBL8890894 | 0.80 | ALDH1A1 (0.36) | PYGLTSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL8889889 | 0.79 | ALDH1A1 (0.35) | PYGLTSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL8891397 | 0.79 | SCN9A (0.45) | TSHRALDH1A1MAPTGSK3BADK | |
| SCHEMBL8889956 | 0.74 | GSK3B (0.35) | KDM4EALDH1A1MAPTKMT2AGSK3B | |
| SCHEMBL8889903 | 0.69 | GSK3B (0.36) | PYGLTSHRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |