Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ADK | P55263 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890894 | 0.91 | ALDH1A1 (0.36) | GLAGSK3BALDH1A1ADKSCN9A | |
| SCHEMBL8891676 | 0.90 | ALDH1A1 (0.37) | GLAGSK3BALDH1A1ADKSCN9A | |
| SCHEMBL8890228 | 0.89 | SCN9A (0.37) | GLAGSK3BALDH1A1SCN9A | |
| SCHEMBL8888951 | 0.84 | SCN9A (0.48) | GLAALDH1A1SCN9A | |
| SCHEMBL7415758 | 0.84 | ACE (0.36) | KDM4E | |
| SCHEMBL8889889 | 0.83 | ALDH1A1 (0.35) | GLAGSK3BALDH1A1ADKSCN9A | |
| SCHEMBL8890236 | 0.82 | ALDH1A1 (0.52) | GSK3BALDH1A1ADKTSHRMAPT | |
| SCHEMBL8891347 | 0.82 | CCKBR (0.43) | — | |
| SCHEMBL8890923 | 0.82 | PYGL (0.39) | GSK3BALDH1A1ADKTSHRMAPT | |
| SCHEMBL8891397 | 0.81 | SCN9A (0.45) | GSK3BALDH1A1ADKSCN9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |