Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 5/20 | 0.43 |
| ▸ | ADK | P55263 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891676 | 0.85 | ALDH1A1 (0.37) | SCN9AGSK3BADKALDH1A1MAPT | |
| SCHEMBL8890217 | 0.81 | GLA (0.36) | SCN9AGSK3BADKALDH1A1MAPT | |
| SCHEMBL8890236 | 0.81 | ALDH1A1 (0.52) | GSK3BADKXIAPALDH1A1MAPT | |
| SCHEMBL8889889 | 0.80 | ALDH1A1 (0.35) | SCN9AGSK3BADKALDH1A1TSHR | |
| SCHEMBL8891347 | 0.79 | CCKBR (0.43) | — | |
| SCHEMBL8888951 | 0.79 | SCN9A (0.48) | SCN9AALDH1A1CNR1 | |
| SCHEMBL8890923 | 0.79 | PYGL (0.39) | GSK3BADKALDH1A1MAPTTSHR | |
| SCHEMBL30157200 | 0.72 | L3MBTL1 (0.38) | SCN9AL3MBTL1ALDH1A1THRBTSHR | |
| SCHEMBL25552348 | 0.72 | L3MBTL1 (0.38) | SCN9AL3MBTL1ALDH1A1THRBTSHR | |
| SCHEMBL7420944 | 0.67 | PYGL (0.49) | XIAPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |