Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891181 | 0.87 | KMT2A (0.40) | SHBGALDH1A1GAAL3MBTL1PLA2G2A | |
| SCHEMBL16429122 | 0.85 | KEAP1 (0.52) | DCLRE1BTSHRCYP2C9HIF1AKEAP1 | |
| SCHEMBL11823508 | 0.84 | DCLRE1B (0.46) | DCLRE1BTSHRCYP2C9HIF1AKEAP1 | |
| SCHEMBL8891670 | 0.84 | PLA2G2A (0.50) | HTTTSHRALDH1A1KDM4EPLA2G2A | |
| SCHEMBL4219021 | 0.84 | PTPN1 (0.53) | DCLRE1BTSHRKEAP1KDM4E | |
| SCHEMBL8767646 | 0.83 | HTT (0.47) | HTTTSHRSHBGKEAP1ALDH1A1 | |
| SCHEMBL28205348 | 0.82 | TSHR (0.61) | HTTTSHRCYP2C9HIF1AALDH1A1 | |
| SCHEMBL10607918 | 0.79 | TSHR (0.48) | HTTTSHRCYP2C9HIF1ARXRA | |
| SCHEMBL65008 | 0.77 | KEAP1 (0.50) | HTTDCLRE1BHIF1AKEAP1ALDH1A1 | |
| SCHEMBL23099927 | 0.76 | KDM4E (0.46) | RXRAALDH1A1KDM4EMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |