Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.62 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890013 | 0.90 | KDM4E (0.61) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL8890403 | 0.89 | SYK (0.57) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL17844308 | 0.84 | KDM4E (0.61) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL17810923 | 0.84 | NPC1 (0.53) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL17810925 | 0.84 | NPC1 (0.53) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL29375753 | 0.84 | SMPD1 (0.75) | KDM4ECA12CA1CA2CA4 | |
| SCHEMBL1029034 | 0.84 | SMPD1 (0.75) | KDM4ECA12CA1CA2CA4 | |
| SCHEMBL31691456 | 0.84 | KDM4E (0.55) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL4314016 | 0.83 | SYK (0.58) | SYKAURKBINCENPKDM4EMAPT | |
| SCHEMBL11271923 | 0.83 | SMPD1 (0.73) | KDM4ECA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |