Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890675 | 0.89 | CYP11B1 (0.50) | CYP11B1CYP11B2RECQLL3MBTL1ALDH1A1 | |
| SCHEMBL8891201 | 0.84 | CYP11B1 (0.45) | CYP11B1CYP11B2RECQLL3MBTL1ALDH1A1 | |
| SCHEMBL8891482 | 0.83 | PDE4D (0.52) | CYP11B1CYP11B2RECQLL3MBTL1ALDH1A1 | |
| SCHEMBL21045668 | 0.83 | TRPC6 (0.55) | CYP11B1CYP11B2ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL8890258 | 0.82 | CYP1A2 (0.47) | L3MBTL1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8890209 | 0.80 | NPC1 (0.44) | ALDH1A1NPSR1CHEK1CYP1A2CYP2C19 | |
| SCHEMBL8889931 | 0.78 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1USP2NPSR1CYP1A2 | |
| SCHEMBL8889603 | 0.78 | ALDH1A1 (0.58) | CYP11B1CYP11B2L3MBTL1ALDH1A1USP2 | |
| SCHEMBL8890700 | 0.77 | ALDH1A1 (0.57) | CYP11B1CYP11B2L3MBTL1ALDH1A1USP2 | |
| SCHEMBL25294459 | 0.74 | CYP1A2 (0.48) | ALDH1A1CYP1A2TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |