Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892224 | 0.93 | NPSR1 (0.45) | LMNASMN1; SMN2HSD17B10HPGDKDM4E | |
| SCHEMBL8891687 | 0.91 | LMNA (0.43) | LMNASMN1; SMN2HSD17B10HPGDKDM4E | |
| SCHEMBL8898777 | 0.91 | ALDH1A1 (0.41) | LMNAHSD17B10HPGDKDM4ENPSR1 | |
| SCHEMBL8891041 | 0.90 | LMNA (0.42) | LMNASMN1; SMN2HSD17B10HPGDKDM4E | |
| SCHEMBL8891913 | 0.86 | KDM4E (0.43) | HPGDKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8891432 | 0.85 | ALDH1A1 (0.37) | LMNASMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL8894254 | 0.84 | NPSR1 (0.44) | LMNASMN1; SMN2HSD17B10HPGDKDM4E | |
| SCHEMBL8893666 | 0.83 | KDM4E (0.35) | SMN1; SMN2HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL8892030 | 0.83 | NPSR1 (0.44) | LMNASMN1; SMN2HSD17B10HPGDKDM4E | |
| SCHEMBL8893342 | 0.83 | ALDH1A1 (0.35) | LMNASMN1; SMN2HPGDKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |