Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891256 | 0.91 | KDM4E (0.34) | KDM4EOPRM1OPRD1TP53CA2 | |
| SCHEMBL8891767 | 0.89 | KDM4E (0.34) | KDM4EOPRM1OPRD1TP53ALDH1A1 | |
| SCHEMBL8891913 | 0.87 | KDM4E (0.43) | KDM4EOPRM1OPRD1TP53CA2 | |
| SCHEMBL8898777 | 0.85 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8891142 | 0.84 | HTT (0.35) | KDM4ECA2ALDH1A1MAPTHPGD | |
| SCHEMBL8891063 | 0.83 | LMNA (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8892045 | 0.82 | CA2 (0.32) | CA2ALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL8890064 | 0.82 | L3MBTL1 (0.43) | TP53CA2ALDH1A1MAPTHPGD | |
| SCHEMBL8892224 | 0.82 | NPSR1 (0.45) | KDM4EOPRM1OPRD1TP53ALDH1A1 | |
| SCHEMBL8893667 | 0.81 | CCR2 (0.32) | KDM4EOPRM1OPRD1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |