Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892270 | 0.93 | KEAP1 (0.39) | ALDH1A1POLBLMNAGAAHTT | |
| SCHEMBL8892844 | 0.91 | ABCC9 (0.39) | ALDH1A1POLBLMNASMN1; SMN2GAA | |
| SCHEMBL8893753 | 0.91 | POLB (0.41) | ALDH1A1POLBGAAHTTKMT2A | |
| SCHEMBL8893620 | 0.90 | ALDH1A1 (0.34) | ALDH1A1POLBLMNASMN1; SMN2GAA | |
| SCHEMBL8891690 | 0.86 | HTT (0.37) | ALDH1A1HTTKMT2ACNR1 | |
| SCHEMBL8893995 | 0.85 | ALDH1A1 (0.41) | ALDH1A1POLBLMNASMN1; SMN2HTT | |
| SCHEMBL8891063 | 0.85 | LMNA (0.43) | ALDH1A1POLBLMNASMN1; SMN2GAA | |
| SCHEMBL8891698 | 0.84 | GAA (0.39) | ALDH1A1LMNAGAAHTTKEAP1 | |
| SCHEMBL8891894 | 0.84 | ALDH1A1 (0.37) | ALDH1A1POLBGAAHTTTBXA2R | |
| SCHEMBL8891142 | 0.84 | HTT (0.35) | ALDH1A1LMNAHTTKMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |