Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 10/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | TYK2 | P29597 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891477 | 0.89 | SLC9A1 (0.31) | SLC9A1 | |
| SCHEMBL8891675 | 0.83 | PTGS2 (0.33) | SLC9A1KDM4EALDH1A1 | |
| SCHEMBL6630014 | 0.81 | FBP1 (0.36) | POLBIKBKBSLC9A1JAK2JAK1 | |
| SCHEMBL8893238 | 0.79 | NPSR1 (0.45) | POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3742227 | 0.78 | POLB (0.44) | POLBIKBKBSLC9A1KDM4EALDH1A1 | |
| SCHEMBL8890199 | 0.73 | IKBKB (0.61) | IKBKBSLC9A1KDM4EALDH1A1PPARG | |
| SCHEMBL13056617 | 0.71 | IKBKB (0.38) | POLBIKBKBKDM4EALDH1A1PPARG | |
| SCHEMBL13056605 | 0.68 | KDM4E (0.38) | POLBIKBKBJAK2JAK1TYK2 | |
| SCHEMBL31008786 | 0.68 | FBP1 (0.39) | POLBIKBKBKDM4EALDH1A1PPARG | |
| SCHEMBL6630011 | 0.67 | IKBKB (0.45) | IKBKBJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |