Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544751 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL27895939 | 0.71 | CYP2E1 (0.35) | CYP19A1 | |
| SCHEMBL27469745 | 0.67 | ALPG (0.33) | CYP19A1 | |
| SCHEMBL27903564 | 0.64 | — | — | |
| SCHEMBL27982363 | 0.64 | MEN1 (0.42) | CYP17A1 | |
| SCHEMBL1412677 | 0.64 | NFKB1 (0.47) | CYP19A1 | |
| SCHEMBL27961586 | 0.62 | NFKB1 (0.45) | CYP19A1 | |
| Ammonia Solution, Strong SCHEMBL27340998 | 0.62 | NFKB1 (0.45) | CYP19A1 | |
| SCHEMBL28900913 | 0.58 | TRIM24 (0.41) | — | |
| SCHEMBL9464877 | 0.56 | CYP3A4 (0.41) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594034-A | ADMINISTERING DIRECT ACTING 5-HYDROXYTRYPTAMINE AGONIST TO MAMMAL | ELI LILLY AND COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| US-5594025-A | Method of inhibiting gastric acid secretion with 5-substituted-3-aminochromane | ELI LILLY AND COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0455510-B1 | Use of 5-HT1A receptor agonist compounds for inhibiting gastric acid secretion | LILLY CO ELI (US) | 1996-11-27 | — | — | EP | disclosed |
| US-5576352-A | Method of inhibiting gastric acid secretion with aryloxypropanolamines | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0444854-B1 | 6-Substituted hexahydrobenz[cd]indoles | LILLY CO ELI (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5470853-A | Useful in modifying the serotonin function in the body | ELI LILLY AND COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| US-5462962-A | Administering to mammals to selectively block biological receptors to treat anxiety or depression | ELI LILLY AND COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| US-5457120-A | Antisecretory and antiserotonine agents | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0392768-B1 | Tetrahydrobenz[C,D] indole serotonin agonists | LILLY CO ELI (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5340838-A | Administering serotonin agonist to mammals | ELI LILLY AND COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-5204340-A | Anxiolytic agents; antidepressants; consumptive disorders,e.g. obesity, alcoholism and smoking; sexual dysfunction | ELI LILLY AND COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5158956-A | Administering serotonin receptor agonist | ELI LILLY AND COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0202024-B1 | ADDITIVE FOR LUBRICATING OILS AND HYDROCARBON FUELS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5096908-A | 5-HT1A agonist | ELI LILLY AND COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0455510-A2 | Use of 5-HT1A receptor agonist compounds for inhibiting gastric acid secretion | ELI LILLY AND COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0444854-A2 | 6-Substituted hexahydrobenz[cd]indoles | ELI LILLY AND COMPANY (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4747963-A | Lubricating oil compositions containing modified succinimides (VII) | CHEVRON RESEARCH COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| US-4666459-A | Modified succinimides (VII) | CHEVRON RESEARCH COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| US-4663062-A | Lubricating oil compositions containing modified succinimides (VII) | CHEVRON RESEARCH COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0202024-A2 | Additive for lubricating oils and hydrocarbon fuels | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |