Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891386 | 0.81 | CYP19A1 (0.31) | — | |
| SCHEMBL27895939 | 0.71 | CYP2E1 (0.35) | ALDH1A1CYP11B1 | |
| SCHEMBL28900913 | 0.69 | TRIM24 (0.41) | ALDH1A1CYP11B1 | |
| SCHEMBL27469745 | 0.67 | ALPG (0.33) | ALDH1A1CYP11B1 | |
| SCHEMBL17541606 | 0.65 | — | — | |
| SCHEMBL27903564 | 0.64 | — | — | |
| SCHEMBL27982363 | 0.64 | MEN1 (0.42) | ALDH1A1CYP11B1 | |
| SCHEMBL1412677 | 0.64 | NFKB1 (0.47) | ALDH1A1CYP11B1 | |
| SCHEMBL28033925 | 0.63 | — | — | |
| SCHEMBL28079712 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084090-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | Sumitomo Pharma Co., Ltd. (JP) | 2025-03-13 | — | — | US | disclosed |
| US-12180213-B2 | Substituted pyrazoles showing serotonin 5-HT receptor activity | SUMITOMO PHARMA CO. LTD. (JP) | 2024-12-31 | — | — | US | disclosed |
| US-12077537-B2 | Capsid inhibitors for the treatment of HIV | GILEAD SCIENCES, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-11680064-B2 | Capsid inhibitors for the treatment of HIV | GILEAD SCIENCES, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| CN-115996925-A | Capsid inhibitors for the treatment of HIV | 吉利德科学公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | Sumitomo Pharma Co., Ltd. (JP) | 2023-01-12 | — | — | US | disclosed |
| US-11466007-B2 | Substituted lactams showing serotonin 5-HT receptor activity | Sumitomo Pharma Co., Ltd. (JP) | 2022-10-11 | — | — | US | disclosed |
| EP-3828182-A1 | FUSED RING LACTAM DERIVATIVES | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| CN-112424195-A | Condensed lactam derivatives | 大日本住友制药株式会社 | 2021-02-26 | — | — | CN | disclosed |
| US-10745401-B2 | Condensed lactam derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| WO-1995011247-A1 | NOVEL TAXOIDS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1995-04-27 | — | — | WO | disclosed |
| US-5344939-A | Esterification | PROTOTEK, INC. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5210272-A | Using a magnesium fluoromalonate to fluoromethylate a carboxylic acid | PROTOTEK, INC. (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0202024-B1 | ADDITIVE FOR LUBRICATING OILS AND HYDROCARBON FUELS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5101068-A | Monofluoromethylation of organic compounds, reaction with amino acids | PROTOTEK INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0442754-A2 | Reagents and methods for stereospecific fluoromethylation | PROTOTEK, INC., (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4747963-A | Lubricating oil compositions containing modified succinimides (VII) | CHEVRON RESEARCH COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| US-4666459-A | Modified succinimides (VII) | CHEVRON RESEARCH COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| US-4663062-A | Lubricating oil compositions containing modified succinimides (VII) | CHEVRON RESEARCH COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0202024-A2 | Additive for lubricating oils and hydrocarbon fuels | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084090-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | HTR1A, HTR5A, TPH1 | ALDH1A1 973/4885CYP11B1 1337/4885 |
| US-12180213-B2 | Substituted pyrazoles showing serotonin 5-HT receptor activity | HTR5A, HTR1A, TPH1 | ALDH1A1 753/4885CYP11B1 324/4885 |
| US-10745401-B2 | Condensed lactam derivative | PSEN1, GRIN1, HDAC1 | ALDH1A1 858/4885CYP11B1 767/4885 |
| US-12077537-B2 | Capsid inhibitors for the treatment of HIV | HAVCR2, MAVS, CD4 | ALDH1A1 3650/4885CYP11B1 4375/4885 |
| US-11466007-B2 | Substituted lactams showing serotonin 5-HT receptor activity | HTR1A, HTR5A, TPH1 | ALDH1A1 973/4885CYP11B1 1337/4885 |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | HTR1A, HTR5A, TPH1 | ALDH1A1 973/4885CYP11B1 1337/4885 |
| US-11680064-B2 | Capsid inhibitors for the treatment of HIV | HAVCR2, MAVS, CD4 | ALDH1A1 3650/4885CYP11B1 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.