Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 6/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890736 | 0.84 | CAMK2D (0.51) | MERTKCAMK2DAURKADAPK3JAK2 | |
| SCHEMBL8889429 | 0.82 | MERTK (0.69) | MERTKADORA3NPY5RADORA2A | |
| Hydrochloric Acid SCHEMBL8911047 | 0.81 | MERTK (0.68) | MERTKCAMK2DNPY5R | |
| SCHEMBL27223391 | 0.81 | CAMK2D (0.68) | MERTKCAMK2DAURKADAPK3JAK2 | |
| SCHEMBL30896225 | 0.81 | CAMK2D (0.68) | MERTKCAMK2DAURKADAPK3JAK2 | |
| SCHEMBL30896236 | 0.79 | MERTK (0.56) | MERTKCAMK2DAURKADAPK3JAK2 | |
| SCHEMBL27223397 | 0.79 | MERTK (0.56) | MERTKCAMK2DAURKADAPK3JAK2 | |
| SCHEMBL30896198 | 0.76 | MERTK (0.76) | MERTKCAMK2DTP53ADORA3NPY5R | |
| SCHEMBL8889650 | 0.76 | MERTK (0.76) | MERTKCAMK2DTP53ADORA3NPY5R | |
| SCHEMBL27223364 | 0.75 | MERTK (0.76) | MERTKCAMK2DNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |