SCHEMBL8891693

SCHEMBL8891693

CS(=O)(=O)c1cccc(C(F)(F)F)c1Cc1ccccc1C(=O)c1cnoc1C1CC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.37
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
DHODH Q02127 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
PIK3CG P48736 1/20 0.34
CACNA1B Q00975 2/20 0.34
F10 P00742 1/20 0.34
P2RX7 Q99572 4/20 0.33
NR1H4 Q96RI1 4/20 0.33
SLC6A3 Q01959 1/20 0.33
NR3C1 P04150 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8891093 0.89 NR3C1 (0.34) SLC9A1DHODHCACNA1BF10P2RX7
SCHEMBL8890546 0.87 NR1H4 (0.35) SLC6A2SLC6A4NR1H4SLC6A3NR3C1
SCHEMBL8891637 0.86 LMNA (0.34) SLC9A1DHODHCACNA1BF10NR3C1
SCHEMBL8890477 0.85 NR3C1 (0.38) DHODHF10NR3C1
SCHEMBL8891589 0.84 DHODH (0.35) SLC6A2SLC6A4DHODHPIK3CDPIK3CB
SCHEMBL8893446 0.84 DHODH (0.34) SLC6A2SLC6A4DHODHPIK3CDPIK3CB
SCHEMBL8891081 0.83 DHODH (0.41) SLC6A2SLC6A4DHODHNR1H4SLC6A3
SCHEMBL8891898 0.83 DHODH (0.41) DHODHCACNA1B
SCHEMBL8891827 0.82 LMNA (0.36) DHODHCACNA1BF10NR1H4NR3C1
SCHEMBL8890152 0.81 LMNA (0.36) DHODHF10NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997028136-A1 BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1997-08-07 WO disclosed