Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 12/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FABP1 | P07148 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891093 | 0.89 | NR3C1 (0.34) | JAK2JAK1TYK2NR3C1LMNA | |
| SCHEMBL8891637 | 0.87 | LMNA (0.34) | JAK2JAK1TYK2NR3C1LMNA | |
| SCHEMBL8890477 | 0.87 | NR3C1 (0.38) | JAK2JAK1TYK2NR3C1LMNA | |
| SCHEMBL8891693 | 0.87 | SLC9A1 (0.37) | NR1H4NR3C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8889324 | 0.84 | HPGD (0.37) | NR1H4SLC22A12LMNASLC6A2SLC6A4 | |
| SCHEMBL8891351 | 0.84 | EPHX2 (0.36) | NR3C1LMNA | |
| SCHEMBL8891669 | 0.84 | ADRA1D (0.35) | NR3C1LMNA | |
| SCHEMBL8891827 | 0.83 | LMNA (0.36) | NR1H4JAK2JAK1TYK2NR3C1 | |
| SCHEMBL8890152 | 0.83 | LMNA (0.36) | JAK2JAK1TYK2NR3C1LMNA | |
| SCHEMBL8891457 | 0.83 | NR1H4 (0.35) | NR1H4SLC22A12SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |