Toluene

Toluene

SCHEMBL8891700

CO[Si](CCCNCCN)(OC)OC.Cc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 8/20 0.43
DRD4 P21917 8/20 0.43
DRD3 P35462 6/20 0.43
CHRM2 P08172 6/20 0.41
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
GRIN1 Q05586 3/20 0.36
GRIN2A Q12879 3/20 0.36
BCHE P06276 2/20 0.36
ACHE P22303 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28340618 0.88 DRD2 (0.43) DRD2DRD4DRD3CHRM2GRIN1
Toluene SCHEMBL15922312 0.85 KIF11 (0.42) CHRM2ACHE
SCHEMBL5603191 0.85 MAPT (0.46) DRD2DRD4DRD3CHRM2GRIN1
SCHEMBL20954192 0.85 CHRM2 (0.40) DRD2DRD4DRD3CHRM2GRIN1
SCHEMBL10579226 0.84 MAPT (0.44) DRD2DRD4DRD3CHRM2GRIN1
SCHEMBL5891867 0.83 CA12 (0.48) CHRM2
SCHEMBL19549 0.83 CA12 (0.48) CHRM2
SCHEMBL5711364 0.83 CA12 (0.48) CHRM2
Toluene SCHEMBL27742396 0.82 KIF11 (0.40) CHRM2ACHE
Hydrochloric Acid SCHEMBL3935447 0.81 CA12 (0.46) CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480311-B Preparation method of molecularly imprinted material for enhancing antibiotic drug effect 天津科技大学 2022-04-01 CN disclosed
CN-112480311-A Preparation method of molecularly imprinted material for enhancing antibiotic drug effect 天津科技大学 2021-03-12 CN disclosed
CN-106190987-A A kind of based on the method for norovirus in amination silica gel concentration detection water body 浙江省疾病预防控制中心 2016-12-07 CN disclosed
CN-1612273-A Film capacitor, built-in high-density assembled substrate thereof and method for making said film capacitor HAYAINADA UNIV (JP) 2005-05-04 CN disclosed
WO-1997028898-A1 IMPROVED FILLED POROUS POLYMERS WITH SURFACE ACTIVE AGENTS AND METHODS OF MAKING SAME W.L. GORE & ASSOCIATES, INC. (US) 1997-08-14 WO disclosed