Toluene

Toluene

SCHEMBL28340618

CCCCNCCC[Si](OC)(OC)OC.Cc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 8/20 0.43
DRD4 P21917 8/20 0.43
DRD3 P35462 6/20 0.43
SIGMAR1 Q99720 1/20 0.42
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
HTR1A P08908 1/20 0.37
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
HTR2A P28223 1/20 0.37
HTR7 P34969 1/20 0.37
HTR2B P41595 1/20 0.37
HTR5A P47898 1/20 0.37
MAPT P10636 1/20 0.37
ALOX12 P18054 1/20 0.37
CRHBP P24387 1/20 0.37
HTT P42858 1/20 0.37
CRHR2 Q13324 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL8891700 0.88 DRD2 (0.43) DRD2DRD4DRD3GRIN1GRIN2A
Toluene SCHEMBL16859706 0.83 LMNA (0.47) ALOX12HTT
SCHEMBL3386839 0.83 DRD2 (0.42) DRD2DRD4DRD3SIGMAR1KDM4E
SCHEMBL3383380 0.83 DRD2 (0.42) DRD2DRD4DRD3SIGMAR1KDM4E
Toluene SCHEMBL5879928 0.83 SIGMAR1 (0.57) DRD2DRD4DRD3SIGMAR1ALOX12
SCHEMBL1998994 0.83 LMNA (0.47) MEN1KMT2A
SCHEMBL56471 0.83 LMNA (0.47) MEN1KMT2A
Hydrochloric Acid SCHEMBL1567031 0.81 LMNA (0.46) HTR1AHTR1DHTR1BHTR2AHTR7
SCHEMBL1411794 0.81 LMNA (0.46) HTR1AHTR1DHTR1BHTR2AHTR7
SCHEMBL13240314 0.81 LMNA (0.46) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107286339-B A kind of preparation method and applications of antibacterial silicon rubber 泰州度博迈医疗器械有限公司 2019-10-18 CN disclosed