Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453990 | 0.87 | F10 (0.38) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8892667 | 0.76 | HPGD (0.37) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7461194 | 0.72 | ITGB3 (0.55) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7458570 | 0.72 | NAMPT (0.43) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7461876 | 0.70 | F10 (0.45) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7465104 | 0.69 | EPHX2 (0.50) | MEN1KMT2A | |
| SCHEMBL7461978 | 0.67 | MAOA (0.44) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7462105 | 0.66 | F10 (0.51) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7461848 | 0.64 | NAMPT (0.46) | — | |
| SCHEMBL4669144 | 0.64 | L3MBTL1 (0.48) | F10ITGB3PRSS1PRSS2ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |