Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885291 | 0.84 | RXFP1 (0.48) | LMNAMAPTSMN1; SMN2ALOX12ROCK2 | |
| SCHEMBL6962348 | 0.84 | RAB9A (0.51) | LMNAHTTMAPTSMN1; SMN2ALOX12 | |
| SCHEMBL8887315 | 0.82 | MAPT (0.51) | LMNAHTTMAPTSMN1; SMN2ALOX12 | |
| SCHEMBL8886510 | 0.81 | NPC1 (0.54) | LMNAHTTMAPTSMN1; SMN2ALOX12 | |
| SCHEMBL6958790 | 0.77 | ALDH1A1 (0.60) | LMNAHTTMAPTSMN1; SMN2ROCK2 | |
| SCHEMBL29352046 | 0.75 | NPC1 (0.54) | LMNAHTTMAPTSMN1; SMN2NFKB1 | |
| SCHEMBL6953553 | 0.75 | NPC1 (0.54) | LMNAHTTMAPTSMN1; SMN2NFKB1 | |
| SCHEMBL8887575 | 0.75 | LMNA (0.56) | LMNAHTTMAPTSMN1; SMN2ALOX12 | |
| SCHEMBL6963950 | 0.74 | KMT2A (0.68) | HTTMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL8886524 | 0.74 | ALDH1A1 (0.48) | LMNAHTTMAPTROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |