Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962348 | 0.88 | RAB9A (0.51) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL8886510 | 0.87 | NPC1 (0.54) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL8887575 | 0.85 | LMNA (0.56) | MAPTLMNAALOX12RAB9AKMT2A | |
| SCHEMBL8891928 | 0.82 | LMNA (0.42) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL8886524 | 0.78 | ALDH1A1 (0.48) | MAPTLMNARAB9AKMT2AMEN1 | |
| SCHEMBL8889740 | 0.76 | ALDH1A1 (0.52) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL8891430 | 0.76 | KMT2A (0.63) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL6962768 | 0.76 | ROCK2 (0.59) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL8885291 | 0.75 | RXFP1 (0.48) | MAPTLMNAALOX12NPC1RAB9A | |
| SCHEMBL3297435 | 0.72 | MAPT (0.64) | MAPTLMNAALOX12NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |