Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602616 | 0.92 | TK1 (0.42) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL1687292 | 0.89 | TK1 (0.51) | TK1 | |
| SCHEMBL5086839 | 0.89 | TK1 (0.46) | TK1TYMS | |
| SCHEMBL5486401 | 0.89 | LMNA (0.46) | TK1TYMS | |
| SCHEMBL8892073 | 0.89 | TYMS (0.43) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL7598501 | 0.88 | TK1 (0.41) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2027057 | 0.88 | LMNA (0.49) | TK1TYMS | |
| SCHEMBL20840413 | 0.88 | TK1 (0.40) | TK1TYMS | |
| SCHEMBL14761760 | 0.87 | TK1 (0.40) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2030339 | 0.86 | TK1 (0.38) | TK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633361-A | OLIGONUCLEOTIDES | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5591843-A | 5-modified pyrimidines from palladium catalyzed carbon-carbon coupling | EATON BRUCE (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0702675-A1 | METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0702675-A4 | METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS | UNIV WASHINGTON (US) | 1996-02-02 | — | — | EP | disclosed |
| US-5428149-A | Reacting vinyl and aryl stannanes with 2'-deoxy-5-halo-uridine | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-06-27 | — | — | US | disclosed |
| WO-1994029279-A1 | METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1994-12-22 | — | — | WO | disclosed |