SCHEMBL5086839

SCHEMBL5086839

COc1ccccc1C(c1ccccc1)(c1ccccc1OC)C(O)[C@H]1O[C@@H](n2cc(I)c(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK1 P04183 6/20 0.46
BCHE P06276 3/20 0.42
TYMS P04818 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687292 0.91 TK1 (0.51) TK1
SCHEMBL5486401 0.90 LMNA (0.46) TK1TYMS
SCHEMBL2027057 0.89 LMNA (0.49) TK1TYMS
SCHEMBL20840413 0.89 TK1 (0.40) TK1TYMS
SCHEMBL8892071 0.89 TK1 (0.40) TK1TYMS
SCHEMBL5086844 0.88 TK1 (0.47) TK1BCHETYMS
SCHEMBL2030339 0.88 TK1 (0.38) TK1TYMS
SCHEMBL7602616 0.87 TK1 (0.42) TK1TYMS
SCHEMBL16177317 0.87 TK1 (0.37) TK1TYMS
SCHEMBL10572305 0.87 TK1 (0.47) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067824-A1 SULFORHODAMINE PHOSPHORAMIDITE DYES CEPHEID 2024-02-29 US disclosed
EP-3790931-B1 SULFORHODAMINE PHOSPHORAMIDITE DYES CEPHEID (US) 2023-09-27 EP disclosed
EP-3790931-A1 SULFORHODAMINE PHOSPHORAMIDITE DYES Cepheid (US) 2021-03-17 EP disclosed
WO-2019217470-A1 SULFORHODAMINE PHOSPHORAMIDITE DYES CEPHEID (US) 2019-11-14 WO disclosed
US-20080032413-A1 Oligonucleotide For Detecting Target Dna Or Rna POSTECH FOUNDATION (KR) 2008-02-07 US disclosed
US-7019135-B2 Anti-viral pyrimidine nucleoside analogues UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2006-03-28 US disclosed
WO-2005098036-A1 OLIGONUCLEOTIDE FOR DETECTING TARGET DNA OR RNA POSTECH FOUNDATION (KR) 2005-10-20 WO disclosed
EP-1280813-B1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIV CARDIFF (GB) 2003-11-12 EP disclosed
US-20030176370-A1 Anti-viral pyrimidine nucleoside analogues UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2003-09-18 US disclosed
US-6573247-B1 Prophylaxis or treatment of varicella-zoster virus or cytomegalo virus infections UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2003-06-03 US disclosed
EP-0980377-B1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIV CARDIFF (GB) 2002-07-31 EP disclosed
US-5633361-A OLIGONUCLEOTIDES WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1997-05-27 US disclosed
US-5591843-A 5-modified pyrimidines from palladium catalyzed carbon-carbon coupling EATON BRUCE (US) 1997-01-07 US disclosed
EP-0702675-A1 METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-03-27 EP disclosed
EP-0702675-A4 METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS UNIV WASHINGTON (US) 1996-02-02 EP disclosed
US-5428149-A Reacting vinyl and aryl stannanes with 2'-deoxy-5-halo-uridine WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-06-27 US disclosed
WO-1994029279-A1 METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1994-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176370-A1 Anti-viral pyrimidine nucleoside analogues CCNO, TYMP, TK1 TK1 3/4885BCHE 4249/4885TYMS 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.